CBD (cannabidiol) is a natural compound found in the cannabis plant. The cannabis plant contains hundreds of different compounds, the best known of which are cannabinoids . CBD is one such cannabinoid. It is important to note that CBD is not a psychoactive compound , that is, it does not cause euphoria or intoxication, which is caused by the other main cannabinoid of cannabis, THC (delta-9-tetrahydrocannabinol).

CBD has many potential health benefits and is used by many to alleviate various health problems . Research suggests that CBD may have anti-inflammatory, pain-relieving, anxiety- and stress-reducing , and neurological and mental health effects. In addition, some people find it helpful in supporting the immune system and improving sleep quality.

However, it is important to point out that CBD is not a drug, not a dietary supplement, and HEMPSTER's CBD products cannot have medicinal effects!

Extracted from the cannabis plant, CBD undergoes a purification process so that it can be used in a pure and concentrated form. It is now available in many different product forms, including oils, extracts, capsules and creams.

A special medium, the carrier oil , is used to dilute the high concentration of CBD.

The vehicle, which is the carrier oil, is a vegetable oil that is used to make the CBD extract edible. With this, we can adjust the different concentrations (5%-10%-15%-20%), in addition, the oil increases the viscosity of the finished product, so it can be dispensed more easily using the dropper pipette. The carrier oil can increase the bioavailability and utilization of the active ingredients.

HEMPSTER CBD oils are also special because we use health-promoting vegetable oils as carrier oils that are healing in themselves, but the combination of CBD and vegetable oils represents a new and promising direction in health and well-being.

Our HEMPSTER special carrier oils:

• black cumin seed oil
• raspberry seed oil
• milk thistle seed oil
• sea ​​buckthorn seed oil
• linseed oil
• hemp seed oil
• pumpkin seed oil

In addition, of course, the HEMPSTER product line also includes oils for which we used MCT oil as a carrier oil. Among the CBD oils on the market, this is the best-known and most neutral-tasting carrier oil.

MCT oil is a special oil made from a combination of coconut and palm oil . It was primarily developed for patients who are unable to digest and use traditional fats . Its medium-chain triglycerides are significantly shorter than those of average fats, which is why it is absorbed much faster. As a result , it is not stored as fat in our body , but is used as energy.

Medium-chain fatty acids provide energy faster, so-called also for the brain in the form of ketone bodies .

Unlike traditional oils, this is a quickly digestible and immediate source of energy , which is why it is very popular among athletes. Due to the structure of the fatty acid composition , MCT oils can be digested and broken down much faster than the fatty acids of ordinary oils and fats.

It is also ideal for fans of the keto , low carb and paleo diets .

CBD (cannabidiol) percentage (%) and milligrams (mg) are two different units of measurement that you will usually find on CBD products. These help determine the concentration of CBD in a particular product. Here's what the CBD percentage and mg show.

CBD percentage (%) : The CBD percentage shows what percentage of the total product weight is CBD. For example, if a CBD oil contains 10% CBD, it means that there are 1000 milligrams (1 gram) of CBD in 10 ml of oil, then the CBD is 10% of the whole weight.

More examples:

• There are 6000 milligrams (6gr) of CBD in 30 ml of oil, so CBD is 20% of the whole weight.
• There are 500 milligrams (0.5gr) of CBD in 10 ml of oil, so CBD is 5% of the whole weight.

CBD milligrams (mg): The CBD milligram value shows how much actual CBD in milligrams is in the product serving.

It is important to note that the concentration and dosage of CBD can be customized and may vary from product to product. It's also important to read the product label and directions for use and consult with a healthcare professional to find the right CBD dose and concentration for your individual needs.

The use of CBD can be safely recommended for people over the age of 18, although it is not forbidden that even children can take it, as it has been shown in clinical research.

CBD should not be used by pregnant or breastfeeding women. Please be aware of possible drug interactions. Consult your doctor or pharmacist before use if you have a pre-existing condition or are taking prescription medication.

Source: https://orvosikannabisz.com/cbd/cbd-hasznalati-utmutato/

Studies have shown that CBD has many targets in the body and can therefore exert a variety of effects. Some of these effects have already been confirmed in clinical trials, as well as the fact that this compound affects cytochrome P450 liver enzymes . CBD can inhibit or enhance drugs that are broken down by these enzymes, although the severity of these effects has not yet been studied, says Dr. Sana-Ara Ahmed, a practicing clinical anesthesiologist with training in interventional chronic pain and cannabinoid medicine. in Alberta and Ontario.

Due to the lack of clinical research, there is still a long way to go to understand the nature of these interactions. However, there is already evidence of certain interactions, including:

Blood thinners
There is an increased risk of bleeding in people who take blood-thinning medications such as warfarin, ibuprofen, coumadin, and others. CBD increases the effectiveness of these medications and prolongs the duration of medication, so they should be monitored. Blood thinners should not be combined with CBD without consulting a doctor or pharmacist.

* Clexane is a strong anticoagulant drug widely used in Hungary, with a low risk of interaction, given that its active ingredient (Enoxaparin) is not metabolized by CYP enzymes.

Tranquilizers

A 2006 study found that CBD had a positive effect on the sleep cycle. When CBD is combined with a sedative drug or drug with sedative properties, it has an additive effect, increasing the drug's effectiveness. This interaction should be considered when determining dosage.

The effectiveness of medicines decreases
CBD can reduce the effectiveness of some medications. In addition to exact dosage requirements, the effect of medications used can be affected by taking CBD. Although CBD is hypothesized to reduce the effectiveness of anesthesia, this issue has not yet been thoroughly studied, so it is too early to draw any conclusions.

If someone decides to use CBD oil in addition to the medications they are taking, it is recommended to use CBD oil NOT at the same time as the medications, always AFTER the medications and not before them, with the greatest possible difference (up to several hours) in order to avoid or minimize possible interactions .

CBD has no intoxicating or addictive properties. In Hungary, cannabis derivatives containing less than 0.2% THC are considered safe and legal .

Based on the provisions of WADA (International Anti-Doping Agency), the use of cannabis derivatives is prohibited, with the exception of CBD!

CBD and CBD oil containing it are not subject to the ban , which can also be consumed by professional athletes.

CBD oil acts on the cannabinoid receptors of our endocannabinoid system.

The endocannabinoid system (ECS) is an extremely important and complex biological system found in the human body that performs many important functions.

This system plays a key role in communication between cells and maintaining a healthy balance. The ECS consists of three main components: endocannabinoids, receptors, and enzymes.

Endocannabinoids are compounds that the body produces itself , and they fall into two main types: anandamide and 2-arachidonylglycerol (2-AG). These substances bind to receptors within the body, such as the CB1 and CB2 receptors. CB1 receptors are mostly found in the brain and nervous system, while CB2 receptors are mainly found in the immune system and peripheral tissues.

The endocannabinoid system regulates many important processes , such as nervous system function, immune system responses, pain sensation, appetite, and metabolic control.

The aim of the system is to maintain balance, i.e. to ensure homeostasis in the body.

ECS receptors are activated by endocannabinoids, resulting in a number of biological responses. For example, when endocannabinoids activate the CB1 receptor, it can help reduce pain or anxiety. Activating CB2 receptors can help regulate the functioning of the immune system.

The operation and role of the endocannabinoid system is still the subject of intensive research and has many possible applications in healthcare.

For example, how cannabinoids found in the cannabis plant (such as CBD) can effectively affect ECS function and therefore potentially be used for therapeutic purposes.

So, the endocannabinoid system (ECS) is a complex and important molecular system that regulates and maintains the body's homeostasis, that is, the stability of the internal environment.

Based on current research , CBD can positively affect our endocannabinoid system. CBD (cannabidiol) is a cannabinoid found in the cannabis plant, but we already know that it does not cause any psychoactive effects.

CBD has a number of interesting effects and is one of the compounds that can effectively influence the endocannabinoid system (ECS) detailed above. Here are some of the ways CBD can affect the ECS:

1. Interaction with receptors : CBD can interact with receptors of the ECS, especially CB1 and CB2 receptors, although it does not directly bind to them. This interaction helps regulate the function of these receptors.
2. Regulation of endocannabinoid levels: CBD can affect the metabolism and breakdown of endocannabinoids. This can increase the level of an endocannabinoid called anandamide in the body, which can help maintain emotional balance and relieve pain.
3. Anti-inflammatory effect: CBD has anti-inflammatory properties and can reduce the inflammatory response of the immune system. This can help treat autoimmune diseases or inflammatory disorders.
4. Reducing stress and anxiety: CBD can affect the ECS by directly or indirectly affecting the nervous system. This allows it to help manage anxiety and stress and improve emotional well-being.
5. Pain Relief: The ECS also plays a key role in regulating the sensation of pain, and CBD can be effective in this area as well. CBD can reduce the sensation of pain by directly affecting the functioning of the nervous system and the endocannabinoid system. CBD can affect receptors in the endocannabinoid system, which play a role in regulating pain perception and inflammation, thereby alleviating chronic pain and inflammatory conditions
6. Neuroprotective effects: ECS plays a role in regulating the normal functioning of the nervous system. Research suggests that CBD may have neuroprotective effects, meaning it may protect against nerve cell damage and support the health and function of the nervous system
7. Immune System Support: ECS can affect the function and regulation of the immune system. CBD may have immunomodulatory effects that can support the proper functioning of the immune system and help regulate inflammatory responses.
8. Alleviation of nausea and vomiting : Regular consumption of CBD can have a helpful effect on stomach and intestinal complaints, especially in alleviating nausea and vomiting.
   

It is important to note that the effects of CBD on the ECS can be complex and variable and vary from individual to individual. Research is still ongoing and more knowledge is needed to fully understand how CBD works and its potential medical applications. It is definitely important to use CBD under medical supervision, especially if someone is already taking other medications or has medical conditions that may affect their response to CBD.

A deeper understanding of the relationship between the endocannabinoid system and CBD holds many opportunities in the medical field. Further research and the advancement of science may help to find further solutions to the potential use of ECS and CBD in treating health problems and maintaining a healthy lifestyle.

And CBD is one of the most important cannabinoids in the cannabis plant, which has a long list of health benefits, including how it can effectively influence this amazing internal biological system for our health.

Research and understanding is constantly evolving and will hopefully bring more exciting discoveries in the future.

All active ingredients have the potential to cause side effects. However, CBD has been shown to be a safe and effective compound in both animal and human clinical studies. Mild side effects may include dry mouth, mild drop in blood pressure, diarrhea, loss of appetite, tiredness, or drowsiness. All of these side effects are considered short-term, meaning they only last as long as the CBD is active in the body.

Don't discourage anyone if you experience the opposite effect at first - e.g. even after a cup of fresh coffee, some people report sleepiness and fatigue - this is the completely normal nature and functioning of the CBD and ECS system. The body's receptors learn to handle the active substance, but this learning process takes some time and may cause the opposite effect in the body.

Keep in mind that individual reactions to CBD may vary, so it is recommended to consult a healthcare professional, especially if you are already taking other medications or have health problems.

• Shake the product well before use!
• Press the pump a few times and measure out the desired amount!
• Drop it under your tongue and leave it there for 60 seconds before swallowing.

We have dedicated a separate chapter to the recommended dosage.

CBD (cannabidiol) is becoming an increasingly popular ingredient in cosmetics. Many cosmetic brands and companies recognize CBD's potential for positive effects on skin health and beauty. Here are some important things to know about CBD as a cosmetic ingredient.

CBD and Skin Health:

• Reduces inflammation: CBD has effective anti-inflammatory properties and can help reduce skin irritations and inflammations; thus, it can be useful in the treatment of acne, eczema or rosacea.
• Hydration: CBD hydrates the skin by helping to restore the skin's lipid layer and retain moisture. This can be especially beneficial for people with dry or sensitive skin.
• Anti-aging effects: CBD also contains antioxidants that can help reduce the signs of skin aging. Antioxidants can neutralize free radicals that can damage the skin and promote aging.
  

Forms of CBD Cosmetics:

• CBD oils and serums: These formulas can be conveniently applied directly to the skin or mucous membranes. CBD oils are available in various concentrations and can help treat a variety of skin problems.
• Creams and Balms: Creams and balms containing CBD can be ideal for topical application, such as on dry or irritated areas of the skin.
• Face masks: CBD face masks can be moisturizing, pore-tightening or anti-inflammatory, which can help alleviate various skin problems.
  

Overall, CBD as a cosmetic is an exciting new area in skin care and beauty care. Many people report positive effects on their skin, but since everyone is unique, it's important to experiment and find the products that best suit your needs.

HEMPSTER is one of the best CBD-based brands on the market, with an exceptional collection designed with unique care .

OUR GOAL is to provide our customers with a luxury experience with the power of nature and the innovative use of CBD.

All our HEMPSTER products comply with EU regulations, have CPNP registration and information documentation, so their use is completely safe.

The CPNP system (Cosmetics Product Notification Portal) is an important tool for the European cosmetics industry and ensures the safety and quality of cosmetics. Cosmetics containing CBD must also comply with these regulations in order to be safely and legally marketed in the European Union.

Our HEMPSTER products have a CPNP registration number.

Since reactions to CBD vary from person to person, it is advisable to consult with a healthcare professional to determine the appropriate CBD dosage, especially if you are taking other medications or have health issues.

It is worthwhile to fully inform yourself and choose the right product and its dosage based on that. Our CBD guide will help you answer a lot of questions, so please read it carefully before you start taking it. If you have any further questions, write to us using the form below.

For the best effect, we recommend the sublingual dosing method. It is generally recommended to start with a low dose and gradually increase until the desired effect is achieved.

It is worth starting with a dose of 5-10 mg/day, 1-2 drops, and then increasing the dose after a few days if necessary.

This is important because research has shown a so-called BELL-CURVE EFFECT* , which means that the response to CBD produces a bell-curve, i.e. when the amount of CBD has reached a certain limit, its effect drops dramatically.

* THE BELL CURVE EFFECT means that cannabis brings a better therapeutic effect until the dose goes up and reaches the level of the body's optimal dose, with further increases, the therapeutic effects decrease and side effects may occur.

Dosage depends on a lot of things. There is no standard dosage that can be used for everyone, it is recommended that everyone experiment with it individually.

Most often

• From the weight of the individual,
• Depending on the severity of the condition to be treated,
• From the CBD concentration of the product used (%, mg),
• From individual reactions and
• depends on the severity of the disease.

That is why we created a simple, but even more useful dosage calculator , which, depending on which of our products you chose - or was recommended to you by our CBD product selection quiz - will help you determine your ideal daily dose drop by drop, when you are already a regular user of the oil.

Based on body weight, it is worth estimating how much CBD oil dose we may need.

As with most active ingredients, heavier people will need more mg of CBD to experience the same effects as lighter people.

Another important factor in determining the right dosage is our overall health.

The more severe our symptoms, the more mg of CBD we will need to experience the same effect as individuals with less severe symptoms.

Effective doses of CBD can range from just a few milligrams to hundreds of milligrams. In any case, it's worth starting with a small dose, especially if you don't have enough experience with cannabis. It is better to take several smaller doses during the day than one large dose. Use the same dose and dosage for a few days. Observe the effects and adjust the dosage or amount if necessary. Cannabis compounds have biphasic properties , meaning that low and high doses of the same compound can produce opposite effects.

In small doses, CBD is more stimulating; calms in large doses. CBD has no known adverse side effects , but excessive amounts of CBD may be less therapeutically effective than a moderate dose. The ' less is more' rule often holds true when it comes to cannabis therapy.

The right dose of CBD varies from person to person. This is because each person has a different state of their endocannabinoid system.

It is a physiological system in the body that is important in the development and treatment of most known diseases. If this system is not working properly, the balance necessary for health can be upset. This system regulates, among other things, the functioning of the immune system, the digestive system and the nervous system .

CBD can help support the endocannabinoid system to ensure it continues to function properly.

It is best to start with a small dose of CBD and then slowly increase the dose until you get the desired results. You have to listen to your body and observe if you notice any changes. People usually make the mistake of using CBD only for a short period of time for problems that have accumulated over years. Chronic diseases require long-term use in almost all cases, such as e.g. antiepileptic drugs. Since in many cases it is a symptomatic treatment, stopping CBD may cause symptoms to return. The use of CBD often leads to a rapid reduction of complaints, but the body must be given enough time to regenerate. Another common mistake is that some people do not use enough because they are afraid to try a larger dose.

CBD is a non-toxic substance and cannot be fatally overdosed. Even children can take it safely in larger doses, as it has been shown in clinical research.

Source: https://orvosikannabisz.com/cbd/cbd-hasznalati-utmutato/

It depends on the CBD concentrate (500 mg, 1000 mg, 1500 mg) and the volume of the selected product (10 ml, 20 ml, or 30 ml), as this ratio indicates how much CBD the given product contains.

For example:

• 3000 mg CBD in a 30 ml bottle = 10% CBD content
• 1500 mg CBD in a 10 ml bottle = 15% CBD content
• 500 mg CBD in a 10ml bottle = 5% CBD content.

Unfortunately, there are many products available to customers that do not even reach 1-2% CBD content. If we don't inform ourselves, they can easily scam us.

Here is an example:

• 250 mg CBD in a 30 ml bottle = 0.83% CBD content,

obsession

• 500 mg CBD in a 30 ml bottle = 1.67% CBD content,

but even the

• Even the 1000 mg CBD in a 30 ml bottle contains only 3.33% CBD.

We buy the given product in good faith in the hope of getting better and we don't understand why there is no meaningful change.

Therefore, CBD education and understanding and finding the most ideal dosage for us are very important.

A dropper pipette is a device for dispensing CBD oil. In general, a pipette dropper can contain 1 ml of solution.

If a 10 ml bottle contains 1000 mg of CBD (10%), then a 1 ml pipette contains 100 mg of CBD.

Doses depending on CBD content:

• For 5% CBD oil: 1 drop contains 2.5 mg of CBD
• For 10% CBD oil: 1 drop contains 5 mg of CBD
• For 15% CBD oil: 1 drop contains 7.5 mg of CBD.

That is, the more serious our condition, the more it is worth choosing a product with a higher CBD content, so that we can accurately measure the amount taken during dosing.

As we wrote earlier, the correct dosage can be set taking into account many factors.

According to previous users of CBD oil, experimenting with very small doses is the most effective way to find the right dose for us. Always record the amount taken and increase or decrease the dose next time.

It is worth starting with a dose of 5-10 mg/day, 1-2 drops, and then increasing the dose after a few days if necessary.

If you want to calculate how many drops we recommend to use per day based on your body weight, the severity of the condition and the dosage content of the product you want to buy, enter your data into the dosage calculator and we will help you find the most optimal dosage.

Let's start with a small dose of CBD and observe for 1-3 weeks.

Since cannabinoids are stored in fat, it takes about that long for CBD to be absorbed into the body and exert its full effect. This is important because a so-called "bell curve effect" or a two-phase effect prevails with the dosage of cannabis. Cannabis compounds have biphasic properties, meaning that low and high doses of the same substance can have opposite effects.

There are no known serious side effects of CBD in normal doses, but drug interactions can be problematic in the case of higher doses. Excessive amounts of CBD may be less effective therapeutically than a moderate dose.

In the case of cannabis therapy, the "less is more" approach often prevails.

This means that cannabis brings a better therapeutic effect until the dose is increased and reaches the level of the patient's optimal dose, but with further increases, the therapeutic effects decrease and side effects may occur. Finding the optimal dose is essential for patients because cannabis cannot be dosed like a traditional medicine.

"Cannabis therapies are personalized medicine. No doctor can tell you the perfect dose, but he can help you develop the right therapy.” Dr. Dustin Sulak

If the effects disappear or seem to decrease after a good period, it may mean that the optimal dose for the patient has been exceeded.

Cannabinoid receptors can become dysfunctional if too much cannabinoids are introduced into the system * .

We need about 1-3 weeks to see the full results of previous dose increases - so if we increase too quickly, we won't see the full results before we add again.

So after a while it accumulates and e.g. in autistic children – who are very sensitive – we see that an excess of even half a mg can throw them out of the therapeutic window (the dose range in which CBD is therapeutically effective). So let's start very low.

If there is NO result with one dose (NOTHING at all, even the smallest positive change counts as a result), then we can increase the dose and follow the same process.

If there is any change - then we wait on that dose - at least three weeks or more until we get a very good idea of ​​how that particular dose is working. (In severe cases, the dose can be increased more quickly). Then we increase the dose further - using the same procedure.

If we do not get a better result after the added dose - we return to the previous dose. If the positive effects stop, restart the dosage (two days of oil-free - or more) and start again at the dose with which you first had good results, depending on how long you used the dose that affected the receptors "saturated".

*The so-called restart or wash out can help re-sensitize the receptors. For example, after 3 weeks of using CBD oil, a 4-5 day rinse. During this period, we completely suspend the use of CBD oil. The restart can be started with a much lower dose, even half as much, because in this case the receptors will be much more sensitive, so the same effect can be achieved with a lower dose.

Example:
Someone uses an oil containing 3 mg/drop of active ingredient and increases it every 3-4 days. By the time the body is saturated, it may be several drops beyond the point that was ideal, so you may have to return to a much smaller dose. You can always return to larger doses slowly and carefully. This way we can find the "limits of the therapeutic window".
Let's say someone receives 11 mg and slowly increases (1 mg/day). When we see the first signs of a decrease or deterioration of the therapeutic effects (say at 20 mg), then we know where the therapeutic range is, within which to experiment. We find that if we increase the dose and there are no better results with the new doses, we can go back to the previous level and stay there. Chances are there will be the right dose somewhere.

Example:
The subject has been receiving a dose of 16 mg/day for a long time and his condition is starting to deteriorate. So the body was getting just a tiny bit more with each dose than it needed and it took a long time for those many small extra doses to build up in the body, so the dose should probably be brought back to 14 or 15 mg.
If someone increases too quickly, they may see the current good effect due to a previous lower dose, which is why they have to wait longer with 1-1 doses.
According to a medical observation, after restarting, it is possible to start again with half of the last working dose and even achieve better results.

Data from research on dosage (see e.g. CBD dosage for anxiety) are informative. According to the law, they do not mean that everyone will need that much, they only serve as a guide, for example, how long it is worth to go with one dose.

EVERY DOSAGE IS INDIVIDUAL.

There is no predetermined dose in any case. There are therapeutic ranges that can provide a closer clue in the case of certain diseases, but everyone has to find the personalized dose for themselves.

Overdosing on CBD is almost impossible. Due to the volume of the packaging, it is not possible to take the amount that would be too large a dose for a human body.

If you experience side effects, reduce the dose.

All of these side effects are considered short-term, meaning they only last as long as the CBD is active in the body.

It takes time for CBD to start working (sometimes a long time). Thanks to some over-the-top marketing campaigns and hype, there are a lot of misguided expectations about how CBD's effects "feel" and how long it takes for them to occur.

It is true that CBD occasionally produces almost immediately noticeable effects in some users. This is usually attributed to having a very different endocannabinoid system or perhaps experiencing a placebo effect. However, it usually takes a few weeks of continuous use to see the effects, or even more. The misconception that CBD works immediately is harmful because many first-time users are disappointed when they do not experience the desired effects within the first day or even the first week . When using CBD as a treatment, it's important to set realistic expectations and recognize that using it takes time, patience, and awareness.

Source: https://orvosikannasz.com/

CBD will not solve all our problems.

Although many companies would like us to believe otherwise, this is the truth. CBD is not a panacea. Not a miracle product. Millions of people have started using CBD regularly for one reason or another, but the truth is that it doesn't work for everyone.

There are many reasons for this. Some are related to the nature of CBD and the endocannabinoid system; some have to do with the fact that each person has a different, unique lifestyle as well as genetic makeup.

While CBD can make a big difference to your health and well-being, it doesn't work for everyone.

We all have unique endocannabinoid systems that respond differently to CBD.

Like a fingerprint, everyone has a uniquely configured endocannabinoid system (ECR). The EKR is one of the largest molecular systems in the human body and consists of millions of cannabinoid receptors scattered throughout the central and peripheral nervous system. It supports the body in maintaining a stable balance in response to environmental changes.

Everyone's endocannabinoid system is unique in its structure and level of functionality. As with any other system in the body, people may naturally have more or fewer receptors - or these receptors may work differently. There may be differences in the number of endocannabinoids produced or how quickly they are metabolized. Some people's endocannabinoid system is well nourished and supported. In these people, the introduction of CBD may produce barely noticeable effects.

How do we know if our endocannabinoid system needs support? Although there is not enough thorough research to formulate a definitive answer, if we experience a change in our environment, we may need some additional cannabinoid support.

Source: https://orvosikannasz.com/

In order to understand whether CBD can improve sleep, we must first understand what causes poor sleep.

There are several things that can lead to poor sleep. According to the Mayo Clinic, insomnia can be caused by:

• mental health disorders such as anxiety, post-traumatic stress disorder (PTSD) and depression
• medication that can interfere with the sleep-wake cycle
• physical symptoms such as chronic pain and restless legs syndrome
• caffeine, especially if consumed later in the day
• environmental factors such as loud noises or an uncomfortable bed

If your insomnia is caused by external factors or associated symptoms, CBD can help treat the causes of insomnia.

While research on CBD is still in its infancy, some research suggests that CBD can treat anxiety .

A study published in 2019 investigated whether CBD could improve sleep and reduce anxiety. 72 subjects participated in the study, 47 experienced anxiety and 25 experienced poor sleep. Subjects received 25 mg of CBD per day in capsule form. In the first month, 79.2% of patients reported lower anxiety levels and 66.7% reported better sleep.

CBD can also help treat pain that causes sleep disorders. A 2018 review in the journal Frontiers in Pharmacology found that there is quite a lot of evidence to support that CBD reduces pain. By reducing chronic pain, CBD may improve sleep, the authors note.

Other research suggests that CBD affects the sleep cycle. A 2014 study looked at four Parkinson's patients and found that CBD improved symptoms of REM sleep behavior disorder (RBD), when people act unconsciously during sleep. RBD is associated with poor sleep and nightmares.

Summary

In small doses, CBD is a type of stimulant. Test subjects who received low doses of CBD spent more time awake and were less able to fall asleep in studies .

The sleep-promoting effect of CBD probably only occurs at high doses (160-600 mg/day).

Source: https://orvosikannasz.com/

Just as certain medicines or vitamins are only recommended after a meal, in order to maximize the absorption of CBD, you should consume CBD products 30 minutes after a meal.

In one study, British researchers showed in a placebo-controlled study of 12 people that CBD increased many times when consumed at the same time as a high-fat breakfast.

Participants in the experiment had not eaten for at least 10 hours before consuming the CBD and breakfast, and were given 1,500 milligrams of CBD during the experiment. Participants took the CBD 30 minutes after starting breakfast.

The CBD concentration has increased many times

In those who took CBD without breakfast to 330 nanograms/milliliter, while those who took it after breakfast, the concentration of CBD in the blood plasma increased to 1630 nanograms/milliliter.

That is, the systemic bioavailability of CBD increased fourfold after breakfast. By systemic bioavailability, we mean the level of CBD content that exerts its effect when it enters the bloodstream.

This study was part of a series of studies in which the pharmacokinetic effects and correlations of high-dose CBD intake (up to 6000mg) were investigated. According to the study, the high concentration was also well tolerated. Although headache was a common side effect, nausea and drowsiness occurred only to a small extent in the participants of the experiment. No strong or serious side effects occurred, and no one had to stop the study due to side effects.

The results of the investigation

The CBD concentration in the blood reached its maximum 4-5 hours after intake, and a stable CBD concentration was measured even two days later. It can be said that twice daily CBD dosing is enough to achieve a constant level of CBD in the blood.

One explanation is that fat increases the excretion of bile acids, and lipophilic substances, which include cannabinoids, dissolve well in bile acids . That is, bile acid increases the absorption of cannabinoids.

According to another possible explanation, the breakdown of cannabinoids in the liver is delayed, because if taken together with fats, most of the CBDs are absorbed through the intestinal lymphatic system.

The original article can be read in German here: CBD-Konzentration im Blut erhöhet sich mit Fett

Let's learn about the bioavailability of CBD

Bioavailability is a term that refers to the percentage of any drug (compound) that is actually absorbed into the bloodstream. This means that when you take any medicine, herb or supplement, even though the dose contains, for example, 50 mg, much less is actually absorbed. This means that in some cases we have a lot of room for improvement if we want the body to make full use of the applied CBD dose.

The bioavailability of CBD depends on various factors. One is the type of product consumed. For example, edible or swallowed CBD products have a lower absorption rate than sublingual or inhaled CBD products.

Why? Because the body metabolizes CBD through the digestive system, which is full of enzymes and acids that can break down and damage the delicate structure of cannabinoids.

In comparison, the sublingual bioavailability of CBD oil is much higher. If we hold CBD oil under our tongue for 30-60 seconds , it is absorbed directly into the bloodstream via the sublingual artery. This means that your body's natural enzymes and compounds have less time and opportunity to break it down, reducing the amount of CBD that is actually absorbed.

The second factor that specifically affects the bioavailability of CBD oil is the type of carrier oil used. Since our bodies are 60% water, the best CBD absorption rates come from water-soluble (water-soluble, nanoemulsion, etc.) product types.

This is why medium-chain triglycerides, or MCT oil, ensure the best absorption of CBD. MCT has a lower molecular weight than other carriers and is water soluble, which combined allows for maximum CBD absorption.

Just as certain medicines or vitamins are only recommended after a meal, in order to maximize the absorption of CBD, you should consume CBD products 30 minutes after a meal.

Source: https://orvosikannabisz.com

Simply put, if we maximize the absorption of CBD, we maximize its benefits. So, if you want to get the most out of each dose, here are 4 simple ways to increase your CBD absorption.

1. Eat with fatty foods

The smaller the molecule, the better it is absorbed by the body. This simple principle is behind the method of consuming CBD with high-fat snacks or foods (e.g. chocolate, fatty fish, avocado, eggs, cheese ). The molecular structure of CBD is highly soluble in fats, and fatty oils successfully dissolve CBD molecules. Another reason why MCT oil is so popular is that it is a “smaller” fat than most other fats that we would digest and is more easily absorbed.

2. Adding herbs

Like food, certain herbs can increase the bioavailability of CBD.

3. Consume CBD sublingually

Last but not least, when learning how to increase the absorption of CBD, it is important to know that sublingual bioavailability of CBD oil is most effective. Even though the tips we've shared will help you increase CBD absorption, regardless of how you consume it, the sublingual bioavailability of CBD will always prevail.

The bioavailability of CBD when ingested is between 13% and 19% . This indicates that when we ingest 20 mg of CBD, our body absorbs about 3 mg or less of it into the bloodstream.

Perhaps one of the most traditional ways to take CBD is through sublingual oils. CBD oil should be held under your tongue for about 60-90 seconds until it is absorbed by the lining of your mouth.

The sublingual (sublingual) administration of CBD is the most direct into the bloodstream, increasing its general bioavailability and, at the same time, the absorption of CBD. However, many people shy away from sublingual consumption due to the raw, pure and all-natural taste of some CBD oils and extracts.

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Effective doses of CBD can range from just a few milligrams to hundreds of milligrams. In any case, it's worth starting with a small dose, especially if you don't have enough experience with cannabis. It is better to take several smaller doses during the day than one large dose. Use the same dose and dosage for a few days. Observe the effects and adjust the dosage or amount if necessary. Cannabis compounds have biphasic properties , meaning that low and high doses of the same compound can produce opposite effects.

In small doses, cannabis is more stimulating; calms in large doses. CBD has no known adverse side effects , but excessive amounts of CBD may be less therapeutically effective than a moderate dose. The ' less is more' rule often holds true when it comes to cannabis therapy.

The right dose of CBD varies from person to person. This is because each person has a different state of their endocannabinoid system. It is a physiological system in the body that is important in the development and treatment of most known diseases. If this system is not working properly, the balance necessary for health can be upset. This system regulates, among other things, the functioning of the immune system, the digestive system and the nervous system. CBD can help support the endocannabinoid system to ensure it continues to function properly. It is best to start with a small dose of CBD and then slowly increase the dose until you get the desired results. You have to listen to your body and observe if you notice any changes. People usually make the mistake of using CBD only for a short period of time for problems that have built up over years. Chronic diseases require long-term use in almost all cases, such as e.g. antiepileptic drugs. Since in many cases it is a symptomatic treatment, stopping CBD may cause symptoms to return. The use of CBD often leads to a rapid reduction of complaints, but the body must be given enough time to regenerate. Another common mistake is that some people do not use enough because they are afraid to try a larger dose. CBD is a non-toxic substance and cannot be fatally overdosed.

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CBD is a supplement, i.e. it serves the purpose indicated by its name: to supplement or improve an already healthy diet and lifestyle.

It is true that CBD works well for many people, but it is not a universal cure. It can help maintain physical balance, but is not a substitute for poor diet, exercise, lack of sleep, poor emotional hygiene, or withdrawal from community and/or supportive social networks. In order to reap the benefits of CBD and maintain true well-being, all the pieces of the puzzle must be put together.

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CBD has, among other things , anxiolytic, antipsychotic, antidepressant, anticonvulsant and neuroprotective effects on the body. The latter means that it can protect the brain and nervous system from damage that can lead to diseases such as Alzheimer's disease.

In addition , CBD can help reduce anxiety, combat depression, suppress or prevent inappropriate electrical activity in the brain (epilepsy), inhibit inflammation, and perhaps help prevent the development of certain neuropsychiatric disorders.

In short, CBD may be responsible for many of the documented and purported beneficial properties of cannabis.

As noted in the 2012 edition of Philosophical Transactions of the Royal Society B: Biological Sciences, “CBD is a safe compound with a wide range of therapeutic applications, including the treatment of psychiatric disorders.”

But how does it affect sleep? Does it promote good sleep or disturb it? The answer is unfortunately complicated.

In animal studies, different doses of CBD were administered, often directly into specific areas of the brain. A relatively well-documented pattern can be observed: the effect of CBD on the sleep-wake cycle is biphasic.

In other words, CBD appears to have the opposite effect on sleep, depending on the dose used.

Animal experiments

Low doses typically have an activating effect on laboratory rats. Conversely, higher doses of CBD (10-40 mg/kg) typically promote more sleep.

The "total percentage of sleep" increased significantly in rats given higher doses, according to a 2013 study published in the Journal of Psychopharmacology .

However, in a 2006 study, rats given microdoses of CBD spent less time asleep and more time awake during the test period.

Human studies

Smaller studies with healthy volunteers mirror these findings. A higher dose of CBD (600 mg/day) caused subjects to spend more time sleeping in one study .

Even at relatively lower doses (160 mg/day), those volunteers who complained of being unable to fall asleep or stay asleep spent more time sleeping.

In the study, those who received CBD reported sleeping longer with less wakefulness or restlessness. CBD use also affected dream recall, but subjects did not report a "hangover" feeling the next day.

Source: https://orvosikannasz.com/

Autism spectrum disorder (ASD) is a complex neurological condition that can cause a variety of symptoms and behavioral characteristics. Many parents and caregivers are looking for effective and safe solutions to alleviate autism symptoms and improve quality of life. Recently, there has been a growing interest in CBD (cannabidiol) oil, and many studies are investigating its effects on autism spectrum disorder.

What is Autism Spectrum Disorder (ASD)?

Autism spectrum disorder is a condition that encompasses a variety of effects on an individual's social interactions, communication, and behavior. There is a wide range within the autism spectrum, from high-functioning autism (which can affect individuals with high intelligence and excellent abilities) to low-functioning autism (which can involve severe social and communication difficulties). The causes and symptoms of autism spectrum disorder are varied and each individual is unique.

How does CBD oil affect Autism?

Research into CBD oil and other cannabinoids for the relief of autism symptoms is still ongoing, but some promising results have already emerged:

Reducing anxiety and stress: Many autistic individuals have anxiety and stress problems. CBD oil has sedative effects and can help reduce these symptoms.

Fewer and Milder Meltdowns: Meltdowns (intense emotional outbursts) can be common in children and adults with autism. CBD can help alleviate these outbursts and help autistic individuals better manage their emotional reactions.

Better Sleep Quality: Autism can often be associated with sleep problems. CBD can improve sleep quality and help autistic individuals rest better.

Improve communication and social skills: Although more research is needed, some studies suggest that CBD oil may help improve communication and social skills in individuals with autism.

Important notes:

It is important to understand that CBD oil does not cure autism and its effects may vary from person to person. Always consult a doctor or healthcare professional before using CBD, especially for your child or other sensitive individuals. CBD should only be purchased and used from legal sources.
Autism spectrum disorder is a complex and multifaceted condition, and each individual is different. For those interested in CBD oil, it's worth researching the topic and consulting with a healthcare professional to see if this natural approach can help alleviate autism symptoms and improve quality of life.

Multiple sclerosis (MS) is a chronic neurological disease that can often cause lifelong challenges and unpleasant symptoms for those affected. Recently, CBD oil has become increasingly prominent in the treatment of multiple sclerosis, and several studies are investigating the potential benefits of CBD for this disease.

What is Multiple Sclerosis?

Multiple sclerosis is an autoimmune disease that causes damage to the myelin sheath of nerves. As a result, the nerves cannot communicate effectively between the brain and the rest of the body. It can have many symptoms, including muscle weakness, cramps, fatigue, and tenderness.

How Does CBD Oil Affect Multiple Sclerosis?

Reduces inflammation: CBD has strong anti-inflammatory properties. Inflammation plays an important role in the development and progression of multiple sclerosis. CBD can reduce inflammation, which can relieve symptoms and slow the progression of the disease.
Pain relief: Multiple sclerosis is often associated with muscle pain and nerve pain. CBD can be a natural pain reliever and can help alleviate these unpleasant symptoms.
Muscle Relaxation: CBD has muscle relaxant effects that can help relieve muscle spasms. This can be particularly useful for treating symptoms such as cramps and muscle stiffness.
Sleep improvement : CBD can help improve sleep, which is especially important for people living with multiple sclerosis. More restful sleep can help alleviate symptoms and improve quality of life.

Important information
It is important to note that CBD oil cannot cure multiple sclerosis and its effects may vary from person to person. However, for many patients, it can help relieve symptoms and improve quality of life.

Always consult your doctor before using CBD oil to ensure it is safe and appropriate for you.

For people living with multiple sclerosis, CBD oil may be a promising alternative to treat symptoms and improve quality of life. Depending on individual circumstances and symptoms, it may be worth a try to experience the potential benefits of CBD for this autoimmune disease.

This topic is currently being researched, since, however, there is not yet sufficient evidence available, based on the current European and Hungarian legal regulations, no medicinal or other effects can be claimed for CBD or CBD-containing products.